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Dr. Jonathan C.H. Chan



Clinical Assistant Professor
Department of Ophthalmology
The University of Hong Kong.
Tel no. : 2518 1430 / 3962 1405

Email: jonochan@hku.hk

Professional Qualifications:

  • BSc(Med)/MBBS(Hons), University of New South Wales (Australia)
  • FHKAM(Ophthalmology)
  • FCOphthHK
  • FRCSEd(Ophth)

Grant Records (as Principle grant-holder):

  1. Food and Health Bureau Health and Medical Research Fund 2015 ($988,892)
  2. University of Hong Kong Seed Funding Programme for Basic Research 2016 ($148,320)
  3. University of Hong Kong Enhanced New Staff Start-up Research Grant 2016 ($380,000)

Research Interests:

  • Glaucoma – minimally invasive glaucoma surgeries (MIGS), modifications of current standard glaucoma surgeries, paediatric glaucoma, wound healing after glaucoma surgeries and its effect on postoperative success, effect of lon-term topical glaucoma treatment on ocular surface
  • Diabetic retinopathy screening
  • Cataract surgeries – effect on angle closure glaucoma

Volunteering Services:

  • 2016 Lifeline Express Visiting Consultant Programme to Xinxiang, Hebei, China
  • 2017 Lifeline Express Visiting Consultant Programme to Enshi, Hubei, China

Key Offices:

  • Honorary Associate Consultant, Department of Ophthalmology, Queen Mary Hospital and Grantham Hospital
  • Honorary Clinical Assistant Professor, Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong
  • Adjunct Assistant Professor, School of Optometry, The Hong Kong Polytechnic University
  • Chief coordinator of diabetic retinopathy (DR) grading training programme and arbitration service for Hospital Authority’s RAMP DR screening programme
  • Departmental Surgical Committee member, HKU-Shenzhen Hospital
  • Training Subcommittee member of the College of Ophthalmologist of Hong Kong
  • Training Curriculum Review Committee member of the College of Ophthalmologist of Hong Kong
  • Visiting Consultant, Lifeline Express
  • Departmental Information Security and Data Management (ISDM) Coordinator, The University of Hong Kong
  • Departmental Equal Opportunity Advisor, The University of Hong Kong

Recent Conferences / Instruction Courses:

  • Complications of ExPress shunt surgery. Tianjin International Ophthalmology Forum 2016.
  • The Feasibility of Diabetic Retinopathy Screening in the Private Sector (Hong Kong). Ophthalmology & Visual Sciences Research Meeting 2016.
  • Diabetic Retinopathy Screening – The Hong Kong Experience. The Cross-Strait Four Regions Ophthalmologic Symposium 2017.
  • Update on Diabetes Management 2017 (course instructor)

Publications:
  1. Chan JC, Lai JS, Lam DS. Nausea and vomiting after phacoemulsification using topical or retrobulbar anesthesia. J Cataract Refract Surg. 2002 Nov; 28(11): 1973-6.

  2. Lai JS, Tham CC, Chan JC, Lam DS. Diode laser transscleral cyclophotocoagulation in the treatment of chronic angle-closure glaucoma: a preliminary study. J Glaucoma. 2003 Aug; 12(4): 360-4.

  3. Lai JS, Tham CC, Chan JC, Yip NK, Tang WW, Li PS, Yeung JC, Lam DS. Scanning laser polarimetry in patients with acute attack of primary angle closure. Jpn J Ophthalmol. 2003 Nov-Dec; 47(6): 543-7.

  4. Lai JS, Tham CC, Chan JC, Lam DS. Phacotrabeculectomy in treatment of primary angle-closure glaucoma and primary open-angle glaucoma. Jpn J Ophthalmol. 2004 Jul-Aug; 48(4): 408-11.

  5. Tham CC, Lai JS, Poon AS, Chan JC, Lam SW, Chua JK, Lam DS. Immediate argon laser peripheral iridoplasty (ALPI) as initial treatment for acute phacomorphic angle-closure (phacomorphic glaucoma) before cataract extraction: a preliminary study. Eye. 2005 Jul; 19(7): 778-83.

  6. Lai JS, Tham CC, Chan JC, Lam DS. Diode laser transscleral cyclophotocoagulation as primary surgical treatment for medically uncontrolled chronic angle closure glaucoma: long-term clinical outcomes. J Glaucoma. 2005 Apr; 14(2): 114-9.

  7. Chan JC, Lai JS, Tham CC. Comparison of postoperative refractive outcome in phacotrabeculectomy and phacoemulsification with posterior chamber intraocular lens implantation. J Glaucoma. 2006 Feb; 15(1): 26-9.

  8. Lai JS, Tham CC, Chan JC. The clinical outcomes of cataract extraction by phacoemulsification in eyes with primary angle-closure glaucoma (PACG) and co-existing cataract: a prospective case series. J Glaucoma. 2006 Feb; 15(1): 47-52.

  9. Lai JS, Tham CC, Chua JK, Poon AS, Chan JC, Lam SW, Lam DS. To compare argon laser peripheral iridoplasty (ALPI) against systemic medications in treatment of acute primary angle-closure: mid-term results. Eye. 2006 Mar; 20(3): 309-14.

  10. Tham CC, Lai JS, Kwong YY, Lam SW, Chan JC, Chiu TY, Lam DS. Correlation of previous acute angle-closure attack with extent of synechial angle closure in chronic primary angle-closure glaucoma patients. Eye. 2008 Apr 18. [Epub ahead of print]

  11. Tham CC, Kwong YY, Leung DY, Lam SW, Li FC, Chiu TY, Chan JC, Chan CH, Poon AS, Yick DW, Chi CC, Lam DS, Lai JS. Phacoemulsification versus combined phacotrabeculectomy in medically controlled chronic angle closure glaucoma with cataract. Ophthalmology. 2008 Dec;115(12):2167-2173.

  12. Tham CC, Kwong YY, Leung DY, Lam SW, Li FC, Chiu TY, Chan JC, Chan CH, Poon AS, Yick DW, Chi CC, Lam DS, Lai JS. Phacoemulsification versus combined phacotrabeculectomy in medically uncontrolled chronic angle closure glaucoma with cataracts. Ophthalmology. 2009 Apr;116(4):725-31.

  13. Tham CC, Kwong YY, Leung DY, Lam SW, Li FC, Chiu TY, Chan JC, Lam DS, Lai JS. Phacoemulsification vs phacotrabeculectomy in chronic angle-closure glaucoma with cataract: complications [corrected]. Arch Ophthalmol. 2010 Mar;128(3):303-11.

  14. Gangwani RA, Chan J, Lee J, Kwong A, Lai JS. Detection of glaucoma in a cohort of chinese subjects with systemic hypertension. J Ophthalmol. 2013;2013:463710.

  15. Lee JW, Chan JC, Chang RT, Singh K, Liu CC, Gangwani R, Wong MO, Lai JS. Corneal changes after a single session of selective laser trabeculoplasty for open-angle glaucoma. Eye (Lond). 2014 Jan;28(1):47-52.

  16. Lee JW, Liu CC, Chan JC, Lai JS. Predictors of success in selective laser trabeculoplasty for Chinese open-angle glaucoma. J Glaucoma. 2014 Jun-Jul;23(5):321-5.

  17. Lee JW, Chan CW, Chan JC, Li Q, Lai JS. The association between clinical parameters and glaucoma-specific quality of life in Chinese primary open-angle glaucoma patients. Hong Kong Med J. 2014 Aug;20(4):274-8.

  18. Lee JW, Liu CC2, Chan JCh, Wong RL, Wong IY, Lai JS. Predictors of success in selective laser trabeculoplasty for primary open angle glaucoma in Chinese. Clin Ophthalmol. 2014 Sep 9;8:1787-91.

  19. Lee JW, Chan CW, Wong MO, Chan JCh, Li Q, Lai JS. A randomized control trial to evaluate the effect of adjuvant selective laser trabeculoplasty versus medication alone in primary open-angle glaucoma: preliminary results. Clin Ophthalmol. 2014 Sep 25;8:1987-92.

  20. Lee JW, Wong RL, Chan JC, Wong IY, Lai JS. Differences in corneal parameters between normal tension glaucoma and primary open-angle glaucoma. Int Ophthalmol. 2014 Nov 25. [Epub ahead of print]

  21. Lee JW, Liu CC, Chan JC, Lai JS. Predictors of success in selective laser trabeculoplasty for normal tension glaucoma. Medicine (Baltimore). 2014 Dec;93(28):e236.

  22. Lee JW, Fu L, Chan JC, Lai JS. Twenty-four-hour intraocular pressure related changes following adjuvant selective laser trabeculoplasty for normal tension glaucoma. Medicine (Baltimore). 2014 Dec;93(27):e238.

  23. Lee JW, Gangwani RA, Chan JC, Lai JS. Prospective study on the efficacy of treating normal tension glaucoma with a single session of selective laser trabeculoplasty. J Glaucoma. 2015 Jan;24(1):77-80.

  24. Wong MO, Lee JW, Choy BN, Chan JC, Lai JS. Systematic review and meta-analysis on the efficacy of selective laser trabeculoplasty in open-angle glaucoma. Surv Ophthalmol. 2015 Jan-Feb;60(1):36-50.

  25. Lee JW, Fu L, Shum JW, Chan JCh, Lai JS. Continuous 24-hour ocular dimensional profile recording in medically treated normal-tension glaucoma. Clin Ophthalmol. 2015 Jan 29;9:197-202.

  26. Lee JW, Ho WL, Chan JC, Lai JS. Efficacy of selective laser trabeculoplasty for normal tension glaucoma: 1 year results. BMC Ophthalmol. 2015 Jan 8;15(1):1.

  27. Gangwani RA, Lee JW, Mo HY, Sum R, Kwong AS, Wang JH, Tsui WW, Chan JC, Lai JS. The Correlation of Retinal Nerve Fiber Layer Thickness With Blood Pressure in a Chinese Hypertensive Population. Medicine (Baltimore). 2015 Jun;94(23):e947.

  28. Lee JW, Shum JJ, Chan JC, Lai JS. Two-Year Clinical Results After Selective Laser Trabeculoplasty for Normal Tension Glaucoma. Medicine (Baltimore). 2015 Jun;94(24):e984.

  29. Choy BN, Zhu MM, Shum JW, Ho WL, Chan JC, Ng AL, Lai JS. Collagen crosslinking in the management of leaking cystic blebs: a prospective study. Graefes Arch Clin Exp Ophthalmol. 2016 Mar;254(3):529-33.

  30. Khor CC,..Chan JC,..Aung T. Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma. Nat Genet. 2016 May;48(5):556-62.

  31. Choy BN, Chan JC, Chien CP, Lai JS. Recurrent acute angle-closure attack due to plateau iris syndrome after cataract extraction with or without argon laser peripheral iridoplasty: a case report. BMC Ophthalmol. 2016 May 26;16:64.

  32. Shum JW, Choy BN, Ho WL, Chan JC, Lai JS. Consensual ophthalmotonic reaction in Chinese patients following augmented trabeculectomy or ExPRESS shunt implantation. Medicine (Baltimore). 2016 Jul;95(29):e4190..

  33. Choy BNK, Wong MOM, Chan JCH, Lai CHY, Lai JSM. ExPRESS Mini-Shunt as a Treatment Alternative for Medically Uncontrolled Steroid-Induced Glaucoma in a Pediatric Patient. Case Rep Ophthalmol 2016;7:270–276.

  34. Shum JWH, Choy BNK,Chan JCH , Ho WL, Jiang BY, Choi WK, Cheung VYT, Lai JSM. Visual Field Compromised In Patients Suffering From Severe Menorrhagia. J Ophthalmol Open Access 2017;1: 1-7.

  35. Shum JS, Lam WW, Choy BN, Chan JC, Ho WL, Lai JS. Development and pilot-testing of Patient Decision Aid for use among Chinese primary open angle glaucoma patients (accepted by BMJ Open Ophthalmology, 2017)

  36. Zhu MM, Lai JSM, Choy BNK, Shum JWH, Lo ACY, Ng ALK, Chan JCH, So KF. Physical exercise and glaucoma: a review on the roles of physical exercise on intraocular pressure control, ocular blood flow regulation, neuroprotection and glaucoma-related mental health (accepted by Acta Ophthalmologica, 2017)